Publications
Braadland, P. R., Ali, A. H., Puchas, P., Juran, B. D., Atkinson, E. J., Schlicht, E. M., Bianchi, J. K., McCauley, B. M., Tjønnfjord, S. K. V., Helgadottir, H., Ueland, P. M., Ulvik, A., Sauer, P., Folseraas, T., Karlsen, T. H., Vesterhus, M., Dill, M. T., Lazaridis, K. N., & Hov, J. R. (2026). Vitamin B6 predicts poor outcomes in geographically distinct populations with primary sclerosing cholangitis. J Hepatol, 85(2), 227–237. https://doi.org/10.1016/j.jhep.2026.03.048
Harris, D. M. M., Bourgonje, A. R., Braadland, P. R., McShane, C., Welz, L., Waschina, S., Ibing, S., Tran, F., Sands, B. E., Dubinsky, M., Suarez-Farinas, M., Argmann, C., Ueland, P. M., McCann, A., Detlie, T. E., Bengtson, M.-B., Kristensen, V., Franke, A., Colombel, J.-F., … Aden, K. (2026). Tryptophan pathway metabotypes associate with disease activity and immune-metabolic dysfunction in inflammatory bowel disease. medRxiv, 2026.05.03.26352309. https://doi.org/10.64898/2026.05.03.26352309
Molinaro, A., Braadland, P. R., Carpino, G., Carreras, A., Nikolaidis, M., Hanzely, P., Beck, K. R., Ali, A. H., Bossen, L., Frank, A., Lundqvist, A., Juran, B. D., Overi, D., Geng, L., Amundsen‑Isaksen, E., Reims, H. M., Björk, I., Grzyb, K., Abildgaard, A., … Hov, J. R. (2026). Gut microbiota-derived imidazole propionate promotes primary sclerosing cholangitis via p38 signalling. Nat Metab, 8(9), 1910–1925. https://doi.org/10.1038/s42255-026-01600-1
Fossdal, G., Braadland, P., Hov, J. R., Husebye, E. S., Folseraas, T., Ueland, P. M., Ulvik, A., Karlsen, T. H., Berge, R. K., & Vesterhus, M. (2025). Mitochondrial dysfunction and lipid alterations in primary sclerosing cholangitis. Scandinavian Journal of Gastroenterology, 60(2), 165–173. https://doi.org/10.1080/00365521.2024.2447521
Jørgensen, S. F., Braadland, P. R., Ueland, T., Fraz, M. S. A., Michelsen, A. E., Holm, K., Osnes, L. T., Trøseid, M., Ueland, P. M., Fevang, B., Aukrust, P., & Hov, J. R. (2025). Tryptophan–kynurenine metabolites associate with inflammation and immunologic phenotypes in common variable immunodeficiency. Journal of Allergy and Clinical Immunology, 156(3), 814–824.e11. https://doi.org/10.1016/j.jaci.2025.04.031
Nendl, A., Raju, S. C., Braadland, P. R., Nordborg, A., Bratseth, V., Broch, K., Jørgensen, S. F., Aukrust, P., Kristiansen, K., Hov, J. R., Trøseid, M., & Awoyemi, A. (2025). Circulating metabolites in patients with chronic heart failure are not related to gut leakage or gut dysbiosis. PLOS ONE, 20(9), e0331692. https://doi.org/10.1371/journal.pone.0331692
Braadland, P. R., Farnes, I., Kure, E. H., Yaqub, S., McCann, A., Ueland, P. M., Labori, K. J., & Hov, J. R. (2024). Indole 3-acetate and response to therapy in borderline resectable or locally advanced pancreatic cancer. Front. Oncol., 14. https://doi.org/10.3389/fonc.2024.1488749
Grimsrud, M. M., Forster, M., Goeppert, B., Hemmrich-Stanisak, G., Sax, I., Grzyb, K., Braadland, P. R., Charbel, A., Metzger, C., Albrecht, T., Steiert, T. A., Schlesner, M., Manns, M. P., Vogel, A., Yaqub, S., Karlsen, T. H., Schirmacher, P., Boberg, K. M., Franke, A., … Folseraas, T. (2024). Whole-exome sequencing reveals novel cancer genes and actionable targets in biliary tract cancers in primary sclerosing cholangitis. Hepatol Commun, 8(7), e0461. https://doi.org/10.1097/HC9.0000000000000461
Lin, W., Gerullat, L., Braadland, P. R., Fournier, A., Hov, J. R., & Globisch, D. (2024). Rapid and Bifunctional Chemoselective Metabolome Analysis of Liver Disease Plasma Using the Reagent 4-Nitrophenyl-2H-azirine. Angewandte Chemie, 136(14), e202318579. https://doi.org/10.1002/ange.202318579
Raju, S. C., Molinaro, A., Awoyemi, A., Jørgensen, S. F., Braadland, P. R., Nendl, A., Seljeflot, I., Ueland, P. M., McCann, A., Aukrust, P., Vestad, B., Mayerhofer, C., Broch, K., Gullestad, L., Lappegård, K. T., Halvorsen, B., Kristiansen, K., Hov, J. R., & Trøseid, M. (2024). Microbial-derived imidazole propionate links the heart failure-associated microbiome alterations to disease severity. Genome Med, 16(1), 27. https://doi.org/10.1186/s13073-024-01296-6
Braadland, P. R., Bergquist, A., Kummen, M., Bossen, L., Engesæter, L. K., Reims, H. M., Björk, I., Grzyb, K., Abildgaard, A., Småstuen, M. C., Folseraas, T., Trøseid, M., Ulvik, A., Ueland, P. M., Melum, E., Line, P.-D., Høivik, M. L., Grønbæk, H., Karlsen, T. H., … Hov, J. R. (2023). Clinical and biochemical impact of vitamin B6 deficiency in primary sclerosing cholangitis before and after liver transplantation. Journal of Hepatology, 79(4), 955–966. https://doi.org/10.1016/j.jhep.2023.05.038
Braadland, P. R., Schneider, K. M., Bergquist, A., Molinaro, A., Lövgren-Sandblom, A., Henricsson, M., Karlsen, T. H., Vesterhus, M., Trautwein, C., Hov, J. R., & Marschall, H.-U. (2022). Suppression of bile acid synthesis as a tipping point in the disease course of primary sclerosing cholangitis. JHEP Reports, 4(11), 100561. https://doi.org/10.1016/j.jhepr.2022.100561
Guldvik, I. J., Braadland, P. R., Sivanesan, S., Ramberg, H., Kristensen, G., Tennstedt, P., Røder, A., Schlomm, T., Berge, V., Eri, L. M., Lilleby, W., Mills, I. G., & Taskén, K. A. (2022). Low Blood Levels of LRG1 Before Radical Prostatectomy Identify Patients with High Risk of Progression to Castration-resistant Prostate Cancer. European Urology Open Science, 45, 68–75. https://doi.org/10.1016/j.euros.2022.09.002
Ramberg, H., Richardsen, E., Souza, G. A. de, Rakaee, M., Stensland, M. E., Braadland, P. R., Nygård, S., Ögren, O., Guldvik, I. J., Berge, V., Svindland, A., Taskén, K. A., & Andersen, S. (2021). Proteomic analyses identify major vault protein as a prognostic biomarker for fatal prostate cancer. Carcinogenesis, 42(5), 685–693. https://doi.org/10.1093/carcin/bgab015
Guldvik, I. J., Zuber, V., Braadland, P. R., Grytli, H. H., Ramberg, H., Lilleby, W., Thiede, B., Zucknick, M., Saatcioglu, F., Gislefoss, R., Kvåle, R., George, A., Grönberg, H., Wiklund, F., Neal, D. E., Gnanapragasam, V. J., Taskén, K. A., & Mills, I. G. (2020). Identification and Validation of Leucine-rich α-2-glycoprotein 1 as a Noninvasive Biomarker for Improved Precision in Prostate Cancer Risk Stratification. European Urology Open Science, 21, 51–60. https://doi.org/10.1016/j.euros.2020.08.007
Serguienko, A., Braadland, P., Meza-Zepeda, L. A., Bjerkehagen, B., & Myklebost, O. (2020). Accurate 3-gene-signature for early diagnosis of liposarcoma progression. Clin Sarcoma Res, 10(1), 4. https://doi.org/10.1186/s13569-020-0126-1
Braadland, P. R., Ramberg, H., Grytli, H. H., Urbanucci, A., Nielsen, H. K., Guldvik, I. J., Engedal, A., Ketola, K., Wang, W., Svindland, A., Mills, I. G., Bjartell, A., & Taskén, K. A. (2019). The β2-Adrenergic Receptor Is a Molecular Switch for Neuroendocrine Transdifferentiation of Prostate Cancer Cells. Mol Cancer Res, 17(11), 2154–2168. https://doi.org/10.1158/1541-7786.MCR-18-0605
Braadland, P. R., & Urbanucci, A. (2019). Chromatin reprogramming as an adaptation mechanism in advanced prostate cancer. Endocr Relat Cancer, 26(4), R211–R235. https://doi.org/10.1530/ERC-18-0579
Braadland, P. R., Giskeødegård, G., Sandsmark, E., Bertilsson, H., Euceda, L. R., Hansen, A. F., Guldvik, I. J., Selnæs, K. M., Grytli, H. H., Katz, B., Svindland, A., Bathen, T. F., Eri, L. M., Nygård, S., Berge, V., Taskén, K. A., & Tessem, M.-B. (2017). Ex vivo metabolic fingerprinting identifies biomarkers predictive of prostate cancer recurrence following radical prostatectomy. Br J Cancer, 117(11), 1656–1664. https://doi.org/10.1038/bjc.2017.346
Braadland, P. R., Grytli, H. H., Ramberg, H., Katz, B., Kellman, R., Gauthier-Landry, L., Fazli, L., Krobert, K. A., Wang, W., Levy, F. O., Bjartell, A., Berge, V., Rennie, P. S., Mellgren, G., Mælandsmo, G. M., Svindland, A., Barbier, O., & Taskén, K. A. (2015). Low β2-adrenergic receptor level may promote development of castration resistant prostate cancer and altered steroid metabolism. Oncotarget, 7(2), 1878–1894. https://doi.org/10.18632/oncotarget.6479
Braadland, P. R., Ramberg, H. A., Grytli, H. H., & Taskén, K. A. (2015). Β-Adrenergic receptor signaling in prostate cancer. Front. Oncol., 4. https://doi.org/10.3389/fonc.2014.00375