Communicating Insights

Hi I’m Peder!

I’m a trained molecular biologist with a great interest in biostatistics, data visualisation and rstats. Currently I’m employed as a postdoc in the Genomics and Metagenomics in Inflammatory Disorders group at the Norwegian PSC Research Center in Oslo.

I’ve made this blog primarily as a repository for my data visualizations and code, which can come in handy when colleagues ask me for help with rstats, coding and biostatistics, or if they simply need inspiration for how they can visualize/tell stories with their data. In fact I sometimes visit the blog to remind myself of how to perform particular tasks in rstats. This blog is also a place where I can rant about various work-related frustrations.

Click here to go to my blog posts

Selected research

Journal of Hepatology, 2024

Clinical and biochemical impact of vitamin B6 deficiency in primary sclerosing cholangitis before and after liver transplantation

We show that vitamin B6 deficiency is prevalent among people with primary sclerosing cholangitis both before and after liver transplantation. Low vitamin B6 associates with altered flux of B6-dependent biochemical pathways and reduced survival both before and after liver transplantation.

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Journal of Hepatology Reports, 2022

Suppression of bile acid synthesis as a tipping point in the disease course of primary sclerosing cholangitis

We found bile acid accumulation-associated suppression of bile acid synthesis in advanced PSC, as indicated by reduced C4. Low C4 associated with poor outcomes. In a subset of the patients, bile acid synthesis was likely suppressed beyond a tipping point where pharmacological suppression may be futile.

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British Journal of Cancer, 2018

Ex vivo metabolic fingerprinting identifies biomarkers predictive of prostate cancer recurrence following radical prostatectomy

Using ex vivo magnetic resonance spectroscopy, we find reduced levels of citrate and spermine in prostate cancer tumors. Low spermine and high levels of the ratio of choline and creatine to spermine in primary tumors were associated with reduced recurrence-free survival after radical prostatectomy.

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Frontiers in Oncology, 2024

Indole 3-acetate and response to therapy in borderline resectable or locally advanced pancreatic cancer

A 2022 Nature study found that circulating levels of microbial 3-IAA associated with improved outcomes in people with metastatic pancreatic cancer undergoing chemotherapy. We measured circulating 3-IAA in borderline resectable or locally advanced pancreatic cancer, but found no association with outcomes.

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Blog

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